Understanding Alzheimer’s Treatments: What Families Need to Know

When a loved one is diagnosed with Alzheimer’s disease, it’s common to ask: Is there a treatment? While there is currently no cure, a number of therapies are available to help manage symptoms, slow progression in early stages, and improve daily quality of life. The Alzheimer’s Association provides helpful guidance on what options are available and how families can make informed choices.

Here’s what you should know.

1. Treatments Are Available, but There’s No Cure

Although Alzheimer’s cannot be reversed or stopped, treatments can make a real difference. Some medications can slow how quickly symptoms get worse, while others help manage issues like memory loss, confusion, and sleep problems. The goal is to help people stay independent and engaged in life as long as possible.

2. New Medications Target the Disease Process

Recent advances have led to new medications that go beyond treating symptoms. These drugs work by targeting amyloid plaques, which are abnormal protein buildups in the brain linked to Alzheimer’s.

Two FDA-approved drugs in this category include:

Donanemab (Kisunla™)
This medication is delivered through monthly IV infusions. It is intended for people in the early phase of Alzheimer’s who have confirmed amyloid in their brain. Research shows that it can help slow down mental and functional decline. Some individuals experience side effects such as swelling in the brain, headaches, or flu-like symptoms.

Lecanemab (Leqembi®)
This drug is also delivered by IV, but every two weeks. Like Donanemab, it is designed for people in the mild stages of Alzheimer’s with confirmed amyloid buildup. It works by clearing amyloid from the brain, which may help preserve thinking and memory. Side effects can include infusion reactions, swelling, or bleeding in the brain.

These medications are only approved for those with mild cognitive symptoms. To be eligible, individuals must undergo diagnostic testing such as a PET scan or a spinal fluid test to confirm the presence of amyloid.

3. Medications That Improve Daily Function

In addition to disease-specific treatments, there are medications that support brain function and improve memory and attention.

Cholinesterase inhibitors like Donepezil, Rivastigmine, and Galantamine help brain cells communicate more effectively. These drugs are often prescribed during the earlier stages of dementia and may help improve memory, language, and problem-solving.

Memantine (Namenda®) works differently and is typically used when dementia has progressed. It can help with attention and the ability to carry out basic daily activities.

These medications don’t stop the disease, but they may help someone function better for a longer period of time.

4. Support for Sleep and Behavioral Symptoms

Changes in sleep and behavior are common with Alzheimer’s. A person may become restless, agitated, or confused later in the day, which is often referred to as sundowning.

To address these concerns, doctors might recommend:

Suvorexant (Belsomra®)
This drug helps people with Alzheimer’s who have trouble falling or staying asleep.

Brexpiprazole (Rexulti®)
Approved for agitation linked to Alzheimer’s, this medication is used when non-drug approaches are not enough. Other antipsychotic drugs may be prescribed in some situations, but they come with risks and should be used carefully.

Before turning to medications, many doctors encourage non-drug approaches. These might include maintaining a consistent sleep schedule, getting daylight in the morning, and limiting naps during the day.

5. Non-Medication Approaches That Help

Many people with dementia benefit from support that doesn’t involve medication. These methods can be just as important as prescriptions when it comes to improving mood and reducing stress.

Examples include:

  • Music, art, and pet therapy
  • Light exercise or daily walks
  • Looking at family photo albums
  • Participating in spiritual or faith-based routines
  • Gentle reminders and structured daily schedules

These activities provide emotional comfort and help people stay connected to who they are.

6. Insurance Coverage Has Expanded

Until recently, access to the newest Alzheimer’s treatments was limited by insurance. Now, Medicare covers both Donanemab and Lecanemab, provided the treatment is part of a clinical registry. Medicare also covers the PET scans needed to confirm an amyloid diagnosis.

These changes make it more affordable for eligible patients to receive diagnosis and treatment without facing large out-of-pocket expenses.

7. Choosing What’s Right for Your Loved One

Every person is different, and so is their Alzheimer’s journey. The best treatment plan depends on several factors, such as:

  • What stage the disease is in
  • The person’s overall health and medical history
  • What symptoms are most troubling
  • What support system is in place at home

Work with your loved one’s doctor or a memory care specialist to decide which options make the most sense. Early planning can help your family prepare for changes and make the most of available treatments.

A Word of Encouragement

It’s normal to feel overwhelmed when you’re caring for someone with Alzheimer’s. The disease affects both memory and identity, and it can be hard to know what to expect. But you’re not alone. Today’s treatment options are improving, and there are real ways to support your loved one throughout the journey.

Whether your family is considering new medications or exploring lifestyle-based care, support is available—and hope is growing.

To explore the full list of treatments, visit the Alzheimer’s Association:
https://www.alz.org/alzheimers-dementia/treatments

Categories: Memory Care